Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508409 | 0.87 | IDO1 (0.47) | TXNRD1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18508439 | 0.86 | MEN1 (0.56) | TXNRD1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18508408 | 0.84 | MERTK (0.43) | TXNRD1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22205280 | 0.81 | TXNRD1 (0.55) | TXNRD1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22264083 | 0.80 | MEN1 (0.58) | TXNRD1MAPTGSTP1GSTM2MEN1 | |
| SCHEMBL18508428 | 0.78 | MEN1 (0.51) | TXNRD1MAPTGSTP1GSTM2MEN1 | |
| SCHEMBL2066899 | 0.72 | TXNRD1 (0.51) | TXNRD1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15472273 | 0.71 | MAPT (0.49) | TXNRD1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10415949 | 0.71 | KMT2A (0.75) | MAPTGSTP1GSTM2MEN1KMT2A | |
| SCHEMBL18508349 | 0.70 | TXNRD1 (0.69) | TXNRD1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027359-A1 | PYRIDINES AND THEIR USE IN THE TREATMENT OF CANCER | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-02-16 | — | — | WO | disclosed |