Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 4/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26520685 | 0.79 | ALDH1A2 (0.34) | PTGER3DRD4MEN1KMT2ATP53 | |
| SCHEMBL15730130 | 0.78 | PDE2A (0.39) | PTGER3CCR4PDE2AMEN1KMT2A | |
| SCHEMBL13131389 | 0.75 | PDE4D (0.39) | PHGDHPTGER3HTR1ADRD2DRD4 | |
| SCHEMBL31479209 | 0.75 | NMT1 (0.46) | PTGER3CCR4PDE2AMEN1KMT2A | |
| SCHEMBL16617267 | 0.75 | NMT1 (0.46) | PTGER3CCR4PDE2AMEN1KMT2A | |
| SCHEMBL13168862 | 0.73 | PDE1A (0.32) | PTGER3HTR1ADRD2DRD4HTR2A | |
| SCHEMBL30240957 | 0.70 | TTR (0.43) | PHGDHPTGER3MEN1KMT2A | |
| SCHEMBL8172855 | 0.69 | MPO (0.47) | — | |
| SCHEMBL31479488 | 0.67 | PTGER3 (0.36) | PTGER3 | |
| SCHEMBL8537036 | 0.67 | CCR4 (0.54) | CCR4PDE2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |