Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.49 |
| ▸ | KDM5C | P41229 | 6/20 | 0.46 |
| ▸ | KDM4A | O75164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KDM6B | O15054 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.43 |
| ▸ | KDM4B | O94953 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215570 | 0.86 | KDM4C (0.40) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL1850714 | 0.86 | KDM4E (0.49) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL1850224 | 0.81 | KDM4C (0.48) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL1846917 | 0.80 | GPR52 (0.57) | KDM4CROCK1 | |
| SCHEMBL1851004 | 0.75 | KDM4E (0.48) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| SCHEMBL28883634 | 0.72 | KDM4C (0.66) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL21310976 | 0.71 | KDM4C (0.54) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL1851534 | 0.70 | S1PR5 (0.51) | S1PR5 | |
| SCHEMBL70700 | 0.69 | KDM4C (0.78) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL29407015 | 0.69 | KDM4C (0.78) | KDM4CKDM5CKDM4AKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |