Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13131718 | 0.90 | REN (0.73) | REN | |
| SCHEMBL18508776 | 0.86 | REN (0.60) | REN | |
| SCHEMBL18508969 | 0.84 | REN (0.70) | REN | |
| SCHEMBL18508911 | 0.83 | REN (0.57) | REN | |
| SCHEMBL18508644 | 0.83 | REN (0.83) | REN | |
| SCHEMBL18508922 | 0.81 | REN (0.63) | REN | |
| SCHEMBL18508997 | 0.81 | REN (0.55) | REN | |
| SCHEMBL18508952 | 0.81 | REN (0.67) | REN | |
| SCHEMBL18508983 | 0.80 | REN (0.53) | REN | |
| SCHEMBL18508664 | 0.79 | REN (0.71) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |