SCHEMBL18509909

SCHEMBL18509909

O=S(=O)(I)c1ccc(-c2c[nH]c3cc(F)ccc23)cc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18498729 0.86 TDO2 (1.00) TDO2
SCHEMBL18509572 0.86 TDO2 (1.00) TDO2
SCHEMBL18498686 0.78 TDO2 (0.81) TDO2
SCHEMBL18510040 0.77 TDO2 (0.81) TDO2
SCHEMBL18498737 0.77 TDO2 (1.00) TDO2
SCHEMBL18509961 0.77 TDO2 (1.00) TDO2
SCHEMBL18510002 0.77 TDO2 (0.68) TDO2
6-Fluoro-3-Phenylindole SCHEMBL3626834 0.77 TDO2 (0.68) TDO2
SCHEMBL18509856 0.76 TDO2 (1.00) TDO2
SCHEMBL18498827 0.76 TDO2 (0.72) TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017025868-A1 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE PFIZER INC. (US) 2017-02-16 WO disclosed