Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 15/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573397 | 0.86 | NR4A2 (0.64) | TDO2NR4A2GPR84 | |
| SCHEMBL20451462 | 0.83 | TDO2 (0.60) | TDO2NR4A2IDO1 | |
| SCHEMBL18510002 | 0.83 | TDO2 (0.68) | TDO2NR4A2IDO1 | |
| SCHEMBL16990272 | 0.81 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL20451398 | 0.81 | TDO2 (0.64) | TDO2IDO1MAP2K4 | |
| SCHEMBL27543264 | 0.79 | TDO2 (0.56) | TDO2NR4A2IDO1GPR84 | |
| SCHEMBL16990293 | 0.79 | TDO2 (1.00) | TDO2 | |
| SCHEMBL18509870 | 0.79 | TDO2 (0.61) | TDO2IDO1 | |
| SCHEMBL15712534 | 0.79 | IMPDH2 (0.71) | TDO2NR4A2IMPDH2 | |
| SCHEMBL21892784 | 0.79 | IMPDH2 (0.58) | TDO2NR4A2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | UNIVERSITY OF SASKATCHEWAN (CA) | 2010-12-16 | — | — | US | disclosed |
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | UNIVERSITY OF SASKATCHEWAN (CA) | 2010-12-16 | — | — | US | disclosed |
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | UNIVERSITY OF SASKATCHEWAN (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317703-A1 | METHOD FOR INHIBITING BRASSININ OXIDASE | BROX, BLVRB, BBOX1 | TDO2 148/4885NR4A2 4324/4885IMPDH2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.