Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313458 | 0.78 | TAAR1 (0.54) | TAAR1HTR2AHRH1 | |
| SCHEMBL169508 | 0.70 | LMNA (0.56) | TAAR1HTR2AHRH1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.69 | LMNA (0.54) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL524108 | 0.69 | LMNA (0.43) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL28444835 | 0.68 | LMNA (0.48) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL27508733 | 0.68 | LMNA (0.48) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL6057707 | 0.67 | TAAR1 (0.41) | TAAR1HTR2AHRH1LMNATDP1 | |
| Methylamine SCHEMBL27931105 | 0.67 | LMNA (0.52) | TAAR1HTR2ALMNAGABBR2GABBR1 | |
| SCHEMBL1263573 | 0.67 | AOC3 (0.48) | TAAR1HTR2AHRH1LMNA | |
| SCHEMBL10904177 | 0.65 | TAAR1 (0.50) | TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044316-A1 | Bifunctional Poly(alkyleneoxides) with Aminoalkyl and Unsaturated Termini and Derivatives Thereof | GELEST, INC. | 2017-02-16 | — | — | US | disclosed |