SCHEMBL524108

SCHEMBL524108

CCC(C[SiH](Cl)Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
CCR5 P51681 1/20 0.41
TAAR1 Q96RJ0 4/20 0.41
CYP2D6 P10635 1/20 0.41
MIF P14174 1/20 0.36
TSHR P16473 1/20 0.36
HKDC1 Q2TB90 1/20 0.35
TRPA1 O75762 1/20 0.35
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
AOC3 Q16853 1/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
CTSD P07339 1/20 0.34
CTSE P14091 1/20 0.34
BACE1 P56817 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1403770 0.84 AOC3 (0.40) LMNACCR5TAAR1CYP2D6TSHR
SCHEMBL169508 0.79 LMNA (0.56) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL22555481 0.78 NR1I2 (0.44) HTR2A
Hypochlorous Acid SCHEMBL11415854 0.78 LMNA (0.56) LMNACCR5TAAR1CYP2D6TSHR
SCHEMBL1533152 0.77 FFAR1 (0.44) CYP2D6MIFTSHRAOC3TDP1
Ammonia Solution, Strong SCHEMBL1640901 0.77 LMNA (0.54) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL9716574 0.76 LMNA (0.41) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL2237751 0.76 LMNA (0.48) LMNACCR5TAAR1CYP2D6MIF
SCHEMBL8964015 0.76 LMNA (0.48) LMNACCR5TAAR1CYP2D6MIF
Methylamine SCHEMBL27931105 0.75 LMNA (0.52) LMNACCR5TAAR1CYP2D6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2405982-B1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING (US) 2013-12-18 EP disclosed
US-8293939-B2 Methods for removing vicinal diols from lactic acid fermentation broth DOW CORNING CORPORATION (US) 2012-10-23 US disclosed
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2012-02-02 US disclosed
EP-2405982-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH Dow Corning Corporation (US) 2012-01-18 EP disclosed
WO-2010104677-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2010-09-16 WO disclosed
US-20090030222-A1 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES WITH SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION 2009-01-29 US disclosed
EP-1979422-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS Dow Corning Corporation (US) 2008-10-15 EP disclosed
WO-2007084245-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION (US) 2007-07-26 WO disclosed
WO-2005034205-A2 SELF ASSEMBLING NANOPARTICLE-POLYMER HYBRIDS DOW CORNING CORPORATION (US) 2005-04-14 WO disclosed
EP-0665256-A2 Pristine phenylpropylalkylsiloxanes DOW CORNING CORPORATION (US) 1995-08-02 EP disclosed
US-5384383-A Pristine phenylpropylalkylsiloxanes DOW CORNING CORPORATION (US) 1995-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH SORD, LDHA, LDHB LMNA 1216/4885CCR5 2068/4885TAAR1 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.