Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159051 | 0.93 | POLB (0.44) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL16559838 | 0.91 | POLB (0.44) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL29333409 | 0.91 | POLB (0.38) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL25933597 | 0.91 | POLB (0.38) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL24355953 | 0.90 | POLB (0.37) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL24440871 | 0.90 | POLB (0.43) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL22845690 | 0.89 | POLB (0.41) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL16559829 | 0.87 | POLB (0.47) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL21841985 | 0.86 | POLB (0.34) | POLBAPEX1HTTTDP1KMT2A | |
| SCHEMBL19497305 | 0.86 | POLB (0.34) | POLBAPEX1HTTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985334-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-3130650-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-15 | — | — | EP | disclosed |