Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333409 | 0.99 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25933597 | 0.99 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25118254 | 0.93 | SRD5A2 (0.35) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL24244887 | 0.93 | POLB (0.33) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19881906 | 0.92 | TDP1 (0.34) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23544524 | 0.92 | TDP1 (0.34) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21675423 | 0.92 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL17485637 | 0.91 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18511121 | 0.90 | POLB (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL21693482 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20230002678-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
| WO-2022084168-A1 | 4,6-DIFLUORODIBENZOTHIOPHENE DERIVATIVES AND LIQUID-CRYSTAL MEDIUM CONTAINING THESE | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | WO | disclosed |