Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18476299 | 0.93 | THRB (0.40) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL18688195 | 0.89 | POLB (0.41) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL21693482 | 0.89 | POLB (0.40) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL18511121 | 0.89 | POLB (0.38) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL18476298 | 0.88 | POLB (0.37) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL16559838 | 0.86 | POLB (0.44) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL22592264 | 0.85 | POLB (0.39) | POLBAPEX1HTTTDP1PTPN11 | |
| SCHEMBL19559099 | 0.85 | POLB (0.39) | POLBAPEX1HTTTDP1PTPN11 | |
| SCHEMBL24440871 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL21289112 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739267-B2 | LC medium | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| EP-3331965-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| US-20200407640-A1 | LC MEDIUM | MERCK PATENT GMBH (DE) | 2020-12-31 | — | — | US | disclosed |