SCHEMBL1851394

SCHEMBL1851394

O=S(=O)(O)SCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.52
ACHE P22303 1/20 0.52
CYP2C19 P33261 1/20 0.48
IDO1 P14902 3/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
BLM P54132 1/20 0.42
GFER P55789 1/20 0.42
PMP22 Q01453 1/20 0.42
CA2 P00918 7/20 0.42
CA1 P00915 6/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28198886 0.98 BCHE (0.50) BCHEACHECYP2C19IDO1NOS3
SCHEMBL21856252 0.82 HRH3 (0.39) BCHEACHELMNAGAACA2
SCHEMBL28351252 0.81 BCHE (0.55) BCHEACHECYP2C19IDO1NOS3
SCHEMBL28667124 0.80 CA2 (0.50) CYP2C19NOS1KDM4EALDH1A1LMNA
SCHEMBL28240553 0.78 BCHE (0.54) BCHEACHEIDO1ALDH1A1GAA
SCHEMBL15664630 0.78 TSHR (0.45) BCHEACHENOS1ALDH1A1LMNA
SCHEMBL27811348 0.78 CA1 (0.44) BCHEACHECYP2C19IDO1NOS3
SCHEMBL9821641 0.77 CA2 (0.52) BCHEACHEIDO1NOS3NOS1
SCHEMBL5467513 0.77 BCHE (0.56) BCHEACHECYP2C19IDO1NOS3
SCHEMBL2929591 0.76 BCHE (0.55) BCHEACHECYP2C19IDO1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2081683-B1 METHODS FOR MANUFACTURING BI-METALLIC CATALYSTS HAVING A CONTROLLED CRYSTAL FACE EXPOSURE HEADWATERS TECH INNOVATION LLC (US) 2011-05-25 EP claimed
US-3966720-A Process for producing desacetoxy cephalosporanic acid compound NIKKEN CHEMICALS CO., LTD. (JA) 1976-06-29 US claimed
JP-60045556-A None JP disclosed
US-5026740-A For transparent or pigmented mixtures FRATELLI LAMBERTI S.P.A. (IT) 1991-06-25 US disclosed
EP-0192967-B1 SULPHURATED DERIVATIVES OF AROMATIC-ALIPHATIC AND ALIPHATIC KETONES AS POLYMERISATION PHOTOINITIATORS FRATELLI LAMBERTI S.p.A. (IT) 1990-08-01 EP disclosed
EP-0192967-A1 Sulphurated derivatives of aromatic-aliphatic and aliphatic ketones as polymerisation photoinitiators FRATELLI LAMBERTI S.p.A. (IT) 1986-09-03 EP disclosed
JP-S6045556-A PRODUCTION OF BENZYLSULFONYL CHLORIDE MITSUBISHI CHEM IND LTD 1985-03-12 JP disclosed
US-3932480-A PHOTOGRAPHY POLAROID CORPORATION (US) 1976-01-13 US disclosed