SCHEMBL28667124

SCHEMBL28667124

O=S(=O)(O)SCCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.50
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
BLM P54132 1/20 0.50
GFER P55789 1/20 0.50
PMP22 Q01453 1/20 0.50
CA1 P00915 3/20 0.45
CA9 Q16790 2/20 0.45
CA5A P35218 1/20 0.45
KEAP1 Q14145 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
NOS1 P29475 1/20 0.44
HDAC3 O15379 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3245281 0.82 RECQL (0.48) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL1851394 0.80 BCHE (0.52) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL15665495 0.79 MAOA (0.53) CA2ALDH1A1LMNACYP3A4CA1
Sulfuric Acid SCHEMBL1607638 0.79 ALDH1A1 (0.65) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL28198886 0.78 BCHE (0.50) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL15664457 0.75 FDPS (0.38) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL5078164 0.74 CA2 (0.46) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL15302869 0.74 HDAC3 (0.47) CA2ALDH1A1KDM4ELMNACYP3A4
SCHEMBL248501 0.73 CA2 (0.53) CA2ALDH1A1KDM4ELMNACYP3A4
Phenylethyl Alcohol SCHEMBL8145578 0.73 TDP1 (0.76) CA2ALDH1A1KDM4ELMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383817-B Synthetic method of thiocoumarin 青岛科技大学 2021-11-09 CN disclosed