Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18514839 | 0.94 | MEN1 (0.38) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18749006 | 0.92 | LMNA (0.41) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514261 | 0.91 | ALDH1A1 (0.39) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18515444 | 0.91 | ALDH1A1 (0.39) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514838 | 0.91 | LMNA (0.37) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514846 | 0.91 | LMNA (0.35) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514847 | 0.91 | LMNA (0.35) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514975 | 0.89 | LMNA (0.40) | LMNAALDH1A1GAAMAPTALOX12 | |
| SCHEMBL18514837 | 0.88 | ALDH1A1 (0.39) | LMNAALDH1A1GAAMAPTNPSR1 | |
| SCHEMBL18514825 | 0.88 | ALDH1A1 (0.37) | LMNAALDH1A1GAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3130584-A1 | AROMATIC COMPOUND AND USES THEREOF | Sumitomo Chemical Company Limited (JP) | 2017-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | LMNA 2808/4885ALDH1A1 1238/4885GAA 3081/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | LMNA 3163/4885ALDH1A1 1416/4885GAA 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.