Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18507100 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL20367410 | 0.77 | PDE9A (0.39) | PDE9A | |
| SCHEMBL18525775 | 0.77 | NUDT1 (0.33) | PDE9A | |
| SCHEMBL21601092 | 0.75 | PDE9A (0.32) | PDE9A | |
| SCHEMBL20372134 | 0.74 | VRK1 (0.36) | PDE9A | |
| SCHEMBL20372243 | 0.71 | CCNC (0.44) | PDE9A | |
| SCHEMBL20361367 | 0.71 | KCNH2 (0.34) | — | |
| SCHEMBL20361143 | 0.71 | KCNH2 (0.34) | — | |
| SCHEMBL20372385 | 0.71 | KCNH2 (0.34) | PDE9A | |
| SCHEMBL20372544 | 0.71 | KCNH2 (0.34) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127801-A1 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2017025917-A1 | 5-(N-BENZYL TETRAHYDROISOQUINOLIN-6-YL) PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2017-02-16 | — | — | WO | disclosed |