Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.54 |
| ▸ | HTR2B | P41595 | 14/20 | 0.54 |
| ▸ | HTR7 | P34969 | 14/20 | 0.54 |
| ▸ | HTR5A | P47898 | 13/20 | 0.54 |
| ▸ | HTR1D | P28221 | 12/20 | 0.54 |
| ▸ | HTR2A | P28223 | 12/20 | 0.54 |
| ▸ | HTR1B | P28222 | 11/20 | 0.54 |
| ▸ | HTR6 | P50406 | 9/20 | 0.54 |
| ▸ | HTR2C | P28335 | 7/20 | 0.54 |
| ▸ | HTR1E | P28566 | 7/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269721 | 0.98 | HTR1A (0.56) | HTR1AHTR2BHTR7HTR5AHTR1D | |
| SCHEMBL3643541 | 0.86 | CA1 (0.67) | HTR7KCNN4APPCA12CA1 | |
| SCHEMBL30599266 | 0.86 | CA1 (0.67) | HTR7KCNN4APPCA12CA1 | |
| SCHEMBL11099503 | 0.86 | CA1 (0.67) | HTR7KCNN4APPCA12CA1 | |
| SCHEMBL21886373 | 0.85 | MEN1 (0.49) | HTR1AHTR2BHTR7HTR5AHTR1D | |
| SCHEMBL29788337 | 0.83 | CA1 (0.71) | HTR7APPCA12CA1CA2 | |
| SCHEMBL21877426 | 0.83 | P2RX7 (0.51) | HTR1AHTR2BHTR7HTR5AHTR1D | |
| SCHEMBL29429633 | 0.83 | CA1 (0.71) | HTR7APPCA12CA1CA2 | |
| SCHEMBL4965869 | 0.83 | P2RX7 (0.49) | HTR1AHTR2BHTR7HTR5AHTR1D | |
| SCHEMBL301996 | 0.83 | CA1 (0.71) | HTR7APPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017026643-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2017-02-16 | — | — | WO | disclosed |