SCHEMBL18516612

SCHEMBL18516612

CCC(=O)Nc1ccc(Oc2ccnc3cc(C(=O)N4CC(O)C4)sc23)c(F)c1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.67
KDR P35968 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307495 0.87 MET (0.68) METKDR
Hydrochloric Acid SCHEMBL307597 0.86 MET (0.67) METKDR
SCHEMBL2539374 0.86 MET (0.59) METKDR
SCHEMBL3561621 0.82 KDR (0.53) METKDR
SCHEMBL3559243 0.82 MET (0.68) METKDR
SCHEMBL2534127 0.81 KDR (0.62) METKDR
SCHEMBL2539528 0.81 KDR (0.62) METKDR
SCHEMBL2534123 0.81 KDR (0.62) METKDR
SCHEMBL307536 0.80 MET (1.00) METKDR
SCHEMBL18516293 0.80 MET (0.79) METKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957498-B1 INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING METHYLGENE INC (CA) 2017-02-15 EP disclosed