Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.64 |
| ▸ | KDR | P35968 | 16/20 | 0.64 |
| ▸ | MST1R | Q04912 | 10/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | FPR1 | P21462 | 1/20 | 0.57 |
| ▸ | FPR3 | P25089 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.57 |
| ▸ | SMO | Q99835 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306299 | 0.88 | MET (0.63) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL29487137 | 0.88 | MET (0.63) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL18516323 | 0.87 | MET (0.71) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL13253651 | 0.87 | MET (0.63) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL10223960 | 0.85 | MET (0.56) | METKDR | |
| SCHEMBL305789 | 0.84 | MET (0.61) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL18516435 | 0.82 | MET (0.57) | METKDRMST1R | |
| SCHEMBL18516649 | 0.81 | MET (0.45) | METKDRMST1RAURKAFPR1 | |
| SCHEMBL18516112 | 0.81 | MET (0.45) | METKDRMST1R | |
| SCHEMBL13167414 | 0.81 | MET (0.79) | METKDRMST1RAURKAFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |