Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856096 | 0.97 | GPR52 (0.54) | GPR52JMJD6SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1854994 | 0.92 | GPR52 (0.52) | GPR52JMJD6SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3211059 | 0.90 | GPR52 (0.57) | GPR52SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1852588 | 0.90 | GPR52 (0.53) | GPR52JMJD6SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1851300 | 0.89 | GPR52 (0.47) | GPR52JMJD6SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1849364 | 0.89 | GPR52 (0.51) | GPR52JMJD6SMN1; SMN2ALDH1A1 | |
| SCHEMBL3215484 | 0.88 | GPR52 (0.55) | GPR52JMJD6SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL1850607 | 0.87 | GPR52 (0.52) | GPR52SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL1851194 | 0.86 | GPR52 (0.70) | GPR52JMJD6SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1849196 | 0.85 | GPR52 (0.52) | GPR52JMJD6SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |