Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 19/20 | 0.64 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516882 | 1.00 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL18496714 | 1.00 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL18516759 | 0.90 | FOLH1 (0.51) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL18516758 | 0.90 | FOLH1 (0.51) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL18496713 | 0.88 | FOLH1 (0.54) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL21176379 | 0.88 | FOLH1 (0.54) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL30003719 | 0.88 | NOD1 (0.48) | FOLH1 | |
| SCHEMBL18655461 | 0.86 | FOLH1 (0.74) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL16518793 | 0.84 | FOLH1 (0.70) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL21176206 | 0.83 | FOLH1 (0.50) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027870-A1 | TRIAZOLE CONJUGATED UREAS, THIOUREAS, CARBAMATES, AND \"REVERSED\" CARBAMATES FOR PSMA-TARGETED IMAGING AGENTS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-16 | — | — | WO | disclosed |