SCHEMBL185170

SCHEMBL185170

C[CH]C(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.50
TAAR1 Q96RJ0 4/20 0.42
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
CYP2D6 P10635 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.39
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21331657 1.00 TRPA1 (0.50) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL9325711 0.80 TRPA1 (0.50) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL5855141 0.79 TRPA1 (0.45) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL5855165 0.79 TRPA1 (0.45) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL22206809 0.78 TRPA1 (0.48) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL1462503 0.76 TRPA1 (0.47) TRPA1TAAR1ADRA2AADRA2CLMNA
SCHEMBL496436 0.76 TRPA1 (0.47) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL10012903 0.76 TRPA1 (0.47) TRPA1TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL1462504 0.76 TRPA1 (0.47) TRPA1TAAR1ADRA2AADRA2CLMNA
SCHEMBL11330098 0.76 TAAR1 (0.41) TRPA1TAAR1ADRA2AADRA2CCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024104384-A1 INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS NUCMITO PHARMACEUTICALS CO. LTD. (CN) 2024-05-23 WO claimed
CN-1891220-A Use of 2-amino-3-alkylpyrimidinone derivatives for producing medicaments SANOFI SYNTHELABO (FR) 2007-01-10 CN claimed
CN-1247567-C 2-amino-3-alkylpyrimidinone derivatives as GSK3 beta inhibitors SANOFI AVENTIS (FR) 2006-03-29 CN claimed
US-6605656-B2 A polyolefin alloy (containing styrene, acrylic, rubber, an ionomers as alloying polymer)blended with a polyamide and manipulated in such a manner as to selectively segregate the polyamide toward the front of melt flow of resin VISTEON GLOBAL TECHNOLOGIES, INC. 2003-08-12 US claimed
US-20020095006-A1 Surface properties in thermoplastic olefin alloys VISTEON GLOBAL TECHNOLOGIES, INC. 2002-07-18 US claimed
EP-1211286-A1 Improved surface properties in thermopastic olefin alloys Visteon Global Technologies, Inc. (US) 2002-06-05 EP claimed
WO-2024132803-A1 FLUORESCENT PHENYL XANTHENE DYES BASF SE (DE) 2024-06-27 WO disclosed
WO-2024132801-A1 XANTHENE COMPOUNDS HAVING A WAVELENGTH IN THE RANGE FROM 650 TO 1200 NM BASF SE (DE) 2024-06-27 WO disclosed
CN-115175967-B Ionic liquids for stabilizing viscosity of silicate-based coatings 巴斯夫欧洲公司 2024-06-14 CN disclosed
US-11987738-B2 C2-C3-alkenyl-substituted rylene imide dyes and curing product of curable silicon resin composition and C2-C3-alkenyl-substituted rylene imide dyes BASF SE (DE) 2024-05-21 US disclosed
WO-2024041944-A1 NOVEL ANTHRAQUINONE-BASED NIR ABSORBERS BASF SE (DE) 2024-02-29 WO disclosed
US-11898075-B2 Yellow light emitting device BASF SE 2024-02-13 US disclosed
EP-4097192-B1 NEW RYLENE DICARBOXIMIDES BASF SE (DE) 2023-11-22 EP disclosed
US-4500740-A Hydrolysis of water-insoluble organic halides UOP INC. (US) 1985-02-19 US disclosed
EP-0086403-A2 2-Oxazolidine-ones MERCK PATENT GmbH (DE) 1983-08-24 EP disclosed
US-4258062-A ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-03-24 US disclosed
US-4171370-A Phenoxy-amino-propanols MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-10-16 US disclosed
US-4136100-A BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES BASF AKTIENGESELLSCHAFT (DE) 1979-01-23 US disclosed
US-4104036-A TO IMPROVE OCTANE RATING ATLANTIC RICHFIELD COMPANY (US) 1978-08-01 US disclosed
US-4006243-A FUNGICIDE, BACTERICIDE, YEAST SCHERING AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987738-B2 C2-C3-alkenyl-substituted rylene imide dyes and curing product of curable silicon resin composition and C2-C3-alkenyl-substituted rylene imide dyes RTN3, C9, RER1 TRPA1 771/4885TAAR1 426/4885ADRA2A 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.