Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848413 | 0.88 | LMNA (0.49) | LMNAPKMHSD17B10L3MBTL1POLB | |
| SCHEMBL1855279 | 0.83 | LMNA (0.45) | LMNAPKMHSD17B10L3MBTL1POLB | |
| SCHEMBL1849577 | 0.70 | GPR52 (0.51) | — | |
| SCHEMBL3209995 | 0.69 | LMNA (0.42) | LMNAPKMHSD17B10L3MBTL1POLB | |
| SCHEMBL1855052 | 0.69 | TAAR1 (0.47) | — | |
| SCHEMBL1850062 | 0.67 | MRGPRX4 (0.57) | MRGPRX4NR4A2MAOB | |
| SCHEMBL3217505 | 0.67 | MAOB (0.52) | LMNAPKMHSD17B10MRGPRX4NR4A2 | |
| SCHEMBL1850678 | 0.67 | GPR52 (0.56) | LMNAPKMHSD17B10MRGPRX4NR4A2 | |
| SCHEMBL1854703 | 0.66 | MAPT (0.45) | L3MBTL1MRGPRX4KMT2AMAOB | |
| SCHEMBL1850131 | 0.65 | MRGPRX4 (0.49) | MRGPRX4NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |