Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441607 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL18383388 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL6824923 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL15499832 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ECA12CA1 | |
| Hydrochloric Acid SCHEMBL31568880 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL5287291 | 0.82 | SLC1A3 (0.52) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL21176781 | 0.82 | SLC1A3 (0.52) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL4247918 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL334444 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL3912679 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488522-B1 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI SCIENCE CO LTD (KR) | 2017-02-15 | — | — | EP | disclosed |