SCHEMBL334444

SCHEMBL334444

N[C@@H](CO)[C@@H](O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
CYP3A4 P08684 2/20 0.55
LMNA P02545 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MARS2 Q96GW9 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
MMP2 P08253 3/20 0.52
RPLP1 P05386 1/20 0.50
RPLP0 P05388 1/20 0.50
RPS17 P08708 1/20 0.50
RPSA P08865 1/20 0.50
RPS2 P15880 1/20 0.50
RPL35A P18077 1/20 0.50
RPL7 P18124 1/20 0.50
RPL17 P18621 1/20 0.50
RPS4Y1 P22090 1/20 0.50
RPS3 P23396 1/20 0.50
RPS12 P25398 1/20 0.50
RPL13 P26373 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725933 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL251728 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL29167395 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL12172739 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL14183583 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL4247918 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL4406664 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
SCHEMBL3912679 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
Hydrochloric Acid SCHEMBL11703545 0.98 ALDH1A1 (0.54) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2
Hydrochloric Acid SCHEMBL10626955 0.98 ALDH1A1 (0.54) ALDH1A1CYP3A4LMNASMN1; SMN2MARS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133248-A1 DIASTEREOMERIC AMINOALCOHOL AND AMINOETHER SALTS OF 2-[(4R,S)-8-FLUORO-2-[4-(3-METHOXYPHENYL)PIPERAZIN-1-YL]-3-[2-METHOXY-5-(TRIFLUOROMETHYL)PHENYL]-3,4-DIHYDROQUINAZOLIN-4-YL]ACETIC ACID AND THEIR USE FOR ENANTIOMERIC SEPARATION AIC246 AG & CO. KG (DE) 2025-06-26 WO claimed
CN-111099993-B Preparation method of (S) -2-hydroxy-3-methoxy-3, 3-diphenyl propionic acid 常州恒邦药业有限公司 2022-03-29 CN claimed
CN-110819000-B Waterproof ventilated membrane of polypropylene 温州大学 2022-02-15 CN claimed
CN-107686488-B Synthesis method of biotin intermediate 浙江医药股份有限公司新昌制药厂 2020-04-28 CN claimed
US-20060020022-A1 Enantioselective separation method PHARMACIA & UPJOHN COMPANY LLC 2006-01-26 US claimed
US-20050020834-A1 Method for preparation of sulphostin and its analogue or intermediates thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-27 US claimed
EP-1457494-A1 PROCESSES FOR PREPARATION OF SULPHOSTIN AND ITS ANALOGUES OR INTERMEDIATES THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2004-09-15 EP claimed
US-4014895-A Method for synthesis of optically active thiolactones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 US claimed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-20250325644-A1 ALK POLYPEPTIDES AND METHODS OF USE THEREOF ELICIO THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4627079-A2 THERMOSTABLE BINDING SCAFFOLDS Nectagen, Inc. (US) 2025-10-08 EP disclosed
US-20050020834-A1 Method for preparation of sulphostin and its analogue or intermediates thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-27 US disclosed
EP-1457494-A1 PROCESSES FOR PREPARATION OF SULPHOSTIN AND ITS ANALOGUES OR INTERMEDIATES THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2004-09-15 EP disclosed
US-20030212012-A1 Pharmaceutically active pyrrolidine derivatives MERCK SERONO SA (CH) 2003-11-13 US disclosed
US-20030171309-A1 Pharmaceutically active pyrrolidine derivatives as bax inhibitors MERCK SERONO SA (CH) 2003-09-11 US disclosed
US-6121460-A Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof DSM N.V. (NL) 2000-09-19 US disclosed
US-4014895-A Method for synthesis of optically active thiolactones SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212012-A1 Pharmaceutically active pyrrolidine derivatives OXTR, CNR1, PRLHR ALDH1A1 3384/4885CYP3A4 1961/4885LMNA 4054/4885
US-20050020834-A1 Method for preparation of sulphostin and its analogue or intermediates thereof SOST, PTMS, FGF23 ALDH1A1 3724/4885CYP3A4 2752/4885LMNA 1125/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A ALDH1A1 3922/4885CYP3A4 1489/4885LMNA 2888/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A ALDH1A1 2964/4885CYP3A4 1365/4885LMNA 1747/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B ALDH1A1 733/4885CYP3A4 2895/4885LMNA 2073/4885
US-20060020022-A1 Enantioselective separation method SLC7A1, SLC10A1, DHCR7 ALDH1A1 350/4885CYP3A4 86/4885LMNA 3541/4885
US-20030171309-A1 Pharmaceutically active pyrrolidine derivatives as bax inhibitors SUCNR1, PYCR1, GLS ALDH1A1 3249/4885CYP3A4 1024/4885LMNA 1490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.