Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498592 | 0.87 | HCAR2 (0.32) | — | |
| SCHEMBL18517869 | 0.84 | GPR119 (0.34) | SCN9AGPR119GAA | |
| SCHEMBL18517695 | 0.83 | GAA (0.31) | GAA | |
| SCHEMBL18498615 | 0.78 | HDAC4 (0.34) | SCN9AGPR119GAA | |
| SCHEMBL6921038 | 0.77 | DPP8 (0.35) | SCN9AGPR119GAA | |
| SCHEMBL12693430 | 0.77 | DPP8 (0.35) | SCN9AGPR119GAA | |
| SCHEMBL21764456 | 0.71 | GPR119 (0.34) | SCN9AGPR119 | |
| SCHEMBL18498606 | 0.70 | HCAR2 (0.33) | — | |
| SCHEMBL13467314 | 0.69 | DPP8 (0.35) | SCN9AGPR119GAA | |
| SCHEMBL12693426 | 0.69 | DPP8 (0.35) | SCN9AGPR119GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025565-A1 | 2-AMINO-7A-PHENYL-3,4,4A,5,7,7A-HEXAHYDROFURO[3,4-B]PYRIDINES AS BACE1 INHIBITORS | H. LUNDBECK A/S (DK) | 2017-02-16 | — | — | WO | disclosed |