Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12693430 | 0.92 | DPP8 (0.35) | GPR119DPP8DPP9GAASCN9A | |
| SCHEMBL6921038 | 0.92 | DPP8 (0.35) | GPR119DPP8DPP9GAASCN9A | |
| SCHEMBL18498615 | 0.84 | HDAC4 (0.34) | GPR119HDAC4DPP8DPP9GAA | |
| SCHEMBL18517697 | 0.84 | SCN9A (0.31) | GPR119GAASCN9A | |
| SCHEMBL21764456 | 0.81 | GPR119 (0.34) | GPR119HDAC4DPP8DPP9SCN9A | |
| SCHEMBL16292790 | 0.80 | BACE1 (0.39) | RORC | |
| SCHEMBL18517695 | 0.78 | GAA (0.31) | GAA | |
| SCHEMBL21527071 | 0.77 | BACE1 (0.36) | GPR119DPP8DPP9SCN9ALMNA | |
| SCHEMBL13467314 | 0.75 | DPP8 (0.35) | GPR119HDAC4DPP8DPP9GAA | |
| SCHEMBL12693426 | 0.75 | DPP8 (0.35) | GPR119HDAC4DPP8DPP9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025565-A1 | 2-AMINO-7A-PHENYL-3,4,4A,5,7,7A-HEXAHYDROFURO[3,4-B]PYRIDINES AS BACE1 INHIBITORS | H. LUNDBECK A/S (DK) | 2017-02-16 | — | — | WO | disclosed |