SCHEMBL18519692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23727040	1.00	HPGD (0.58)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL407899	0.94	HPGD (0.56)	HPGDRECQLKMT2AALDH1A1MAPT
	SCHEMBL968401	0.89	MEN1 (0.56)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL3730650	0.89	HPGD (0.51)	HPGDRECQLKMT2AALDH1A1EPHX1
	SCHEMBL442932	0.89	MEN1 (0.56)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL1249710	0.89	MEN1 (0.56)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL389962	0.86	HPGD (0.54)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL894559	0.86	HPGD (0.54)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL586312	0.86	HPGD (0.54)	HPGDRECQLKMT2AALDH1A1MEN1
	SCHEMBL4842173	0.86	HPGD (0.48)	HPGDRECQLKMT2AALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.