Sugi Predict

Sugi Predict / Compounds / SCHEMBL407899

SCHEMBL407899

SCHEMBL407899

CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.56
▸ RECQL P46063 1/20 0.54
▸ PTPN2 P17706 1/20 0.49
▸ PTPN1 P18031 1/20 0.49
▸ PTPN6 P29350 1/20 0.49
▸ EPHX1 P07099 1/20 0.47
▸ STS P08842 5/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.44
▸ GPR119 Q8TDV5 3/20 0.44
▸ HSD17B10 Q99714 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3730650 0.94 HPGD (0.51) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL18519692 0.94 HPGD (0.58) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL23727040 0.94 HPGD (0.58) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL586312 0.91 HPGD (0.54) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL894559 0.91 HPGD (0.54) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL389962 0.91 HPGD (0.54) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL4842173 0.91 HPGD (0.48) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL1087013 0.86 HPGD (0.60) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL14233196 0.84 HPGD (0.59) HPGDRECQLPTPN2PTPN1PTPN6
SCHEMBL278133 0.84 NR1H2 (0.45) HPGDRECQLPTPN2PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103451-A1 PROCESS FOR PREPARING PYRIMIDINYL BIPYRIDINE COMPOUND AND INTERMEDIATE THEREFOR BEYONDBIO INC (KR) 2026-04-16 — — US disclosed
US-20260078115-A1 ALIPHATIC ACID AMIDE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2026-03-19 — — US disclosed
US-12576087-B2 Aryloxypiperidine pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors MERCK SHARP & DOHME LLC (US) 2026-03-17 — — US disclosed
US-12516056-B2 Compounds for inhibition of janus kinase 1 MANKIND PHARMA LTD. (IN) 2026-01-06 — — US disclosed
US-12503463-B2 Aliphatic acid amide derivative Sumitomo Pharma Co., Ltd. (JP) 2025-12-23 — — US disclosed
US-20250282771-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS Treeline Biosciences, Inc. 2025-09-11 — — US disclosed
EP-4082616-B1 ALIPHATIC ACID AMIDE DERIVATIVE SUMITOMO PHARMA CO LTD (JP) 2025-09-03 — — EP disclosed
US-12371418-B2 Process for preparing pyrimidinyl bipyridine compound and intermediate therefor BEYONDBIO INC. (KR) 2025-07-29 — — US disclosed
EP-4572759-A2 THIAZOLE DERIVATIVES FOR THERAPEUTIC USE Nimml Institute (US) 2025-06-25 — — EP disclosed
US-12331046-B2 CTPS1 inhibitors and uses thereof NIMBUS CLOTHO, INC. (US) 2025-06-17 — — US disclosed
US-5891889-A Inhibitors of farnesyl-protein transferase MERCK & CO., INC. (US) 1999-04-06 — — US disclosed
WO-1999006395-A1 PYRIDYL- AND PYRIMIDYL-HETEROCYCLIC COMPOUNDS INHIBITING OXIDO SQUALENE-CYCLASE ZENECA LIMITED (GB) 1999-02-11 — — WO disclosed
WO-1998028275-A1 NOVEL COMPOUNDS WITH ANALGESIC EFFECT ASTRA PHARMA INC. (CA) 1998-07-02 — — WO disclosed
US-5719166-A TREATING PSYCHOSES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-02-17 — — US disclosed
US-5717100-A Substituted imidazoles having anti-cancer and cytokine inhibitory activity MERCK & CO., INC. (US) 1998-02-10 — — US disclosed
WO-1997038665-A2 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1997-10-23 — — WO disclosed
EP-0532177-B1 Methanoanthracenes as dopamine antagonists ZENECA LTD (GB) 1996-10-16 — — EP disclosed
US-5550136-A ANTAGONISTS OF DOPAMINE D-2 RECEPTORS ZENECA LIMITED (GB) 1996-08-27 — — US disclosed
US-5399568-A Dopamine antagonists IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-03-21 — — US disclosed
EP-0532177-A1 Methanoanthracenes as dopamine antagonists ZENECA LIMITED (GB) 1993-03-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282771-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS BCL2, BCL2L10, BCL2L1 HPGD 2424/4885RECQL 83/4885PTPN2 921/4885
US-12576087-B2 Aryloxypiperidine pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors IDO1, IDO2, TPH1 HPGD 117/4885RECQL 1072/4885PTPN2 395/4885
US-20260103451-A1 PROCESS FOR PREPARING PYRIMIDINYL BIPYRIDINE COMPOUND AND INTERMEDIATE THEREFOR CCND1, CCND2, CDK2 HPGD 666/4885RECQL 1307/4885PTPN2 4806/4885
US-12371418-B2 Process for preparing pyrimidinyl bipyridine compound and intermediate therefor WEE1, GGPS1, WEE2 HPGD 470/4885RECQL 1869/4885PTPN2 4634/4885
US-12503463-B2 Aliphatic acid amide derivative HTR2A, HTR1A, HTR7 HPGD 3167/4885RECQL 2439/4885PTPN2 2527/4885
US-20260078115-A1 ALIPHATIC ACID AMIDE DERIVATIVE HTR1D, HTR1A, HTR7 HPGD 4116/4885RECQL 2370/4885PTPN2 1649/4885
US-12331046-B2 CTPS1 inhibitors and uses thereof CTPS1, CTPS2, ECHS1 HPGD 1139/4885RECQL 1254/4885PTPN2 3380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.