Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952516 | 0.80 | CA2 (0.43) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL13522030 | 0.78 | DPP4 (0.50) | DPP4 | |
| SCHEMBL13337063 | 0.78 | DPP4 (0.50) | DPP4 | |
| SCHEMBL13580025 | 0.78 | DPP4 (0.50) | DPP4 | |
| SCHEMBL19036871 | 0.78 | DPP4 (0.50) | DPP4 | |
| SCHEMBL23056586 | 0.78 | DPP4 (0.50) | DPP4 | |
| SCHEMBL13575189 | 0.77 | ALDH1A1 (0.37) | MAPTSMN1; SMN2GAAALDH1A1FFAR2 | |
| SCHEMBL21424045 | 0.77 | ALDH1A1 (0.37) | MAPTSMN1; SMN2GAAALDH1A1FFAR2 | |
| SCHEMBL21638038 | 0.77 | GAA (0.34) | MAPTSMN1; SMN2RAB9AGAAALDH1A1 | |
| SCHEMBL25139840 | 0.77 | GAA (0.34) | MAPTSMN1; SMN2RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646043-B1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL INC (US) | 2017-02-15 | — | — | EP | disclosed |