SCHEMBL185216

SCHEMBL185216

COc1ccc(N(c2ccc(OC)cc2)c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2cc(N(c4ccc(OC)cc4)c4ccc(OC)cc4)ccc2-3)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.44
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39
BCR P11274 1/20 0.39
RPS6KA2 Q15349 1/20 0.38
GPR3 P46089 1/20 0.37
PDE4D Q08499 1/20 0.37
CES1 P23141 1/20 0.37
PGR P06401 1/20 0.36
NPC1 O15118 1/20 0.35
GAA P10253 2/20 0.35
POLB P06746 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589092 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL259184 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL20159380 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL29352894 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL29353071 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL30182778 1.00 PDK2 (0.44) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL14769865 0.94 PDK2 (0.41) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL19319141 0.94 PDK2 (0.41) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL16996394 0.93 PGR (0.40) PDK2ABL1ABCB1BCRRPS6KA2
SCHEMBL16996425 0.93 PDK2 (0.40) PDK2ABL1ABCB1BCRRPS6KA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478576-B9 ORGANIC ELECTRONIC DEVICE AND DOPANT FOR DOPING AN ORGANIC SEMICONDUCTING MATRIX MATERIAL OSRAM OLED GMBH (DE) 2017-09-06 EP claimed
EP-2478576-B1 ORGANIC ELECTRONIC DEVICE AND DOPANT FOR DOPING AN ORGANIC SEMICONDUCTING MATRIX MATERIAL OSRAM OLED GMBH (DE) 2017-05-31 EP claimed
EP-2443680-B1 METHOD OF MANUFACTURING A HOLE TRANSPORT LAYER WITH P-DOPING SIEMENS AG (DE) 2016-08-10 EP claimed
US-8610113-B2 Material for a hole transport layer with p-dopant SIEMENS AKTIENGESELLSCHAFT (DE) 2013-12-17 US claimed
US-20120146006-A1 MATERIAL FOR A HOLE TRANSPORT LAYER WITH P-DOPANT NOVALED GMBH (DE) 2012-06-14 US claimed
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
US-20250185502-A1 ORGANIC OPTOELECTRONIC COMPONENT, ORGANIC FUNCTIONAL LAYER, AND METHOD FOR PRODUCING AN OPTOELECTRONIC COMPONENT OSRAM OLED GMBH (DE) 2025-06-05 US disclosed
WO-2025100171-A1 CHARGE-TRANSPORTING VARNISH AND CHARGE-TRANSPORTING VARNISH FOR QUANTUM DOT ELECTROLUMINESCENT ELEMENT 日産化学株式会社 2025-05-15 WO disclosed
US-12302747-B2 Optoelectronic component, organic functional layer, and method for producing an optoelectronic component OSRAM OLED GMBH (DE) 2025-05-13 US disclosed
WO-2025084125-A1 CHARGE-TRANSPORTING INK COMPOSITION AND INK COMPOSITION FOR UPPER LAYER FILM OF QUANTUM DOT LAYER 日産化学株式会社 2025-04-24 WO disclosed
WO-2025041715-A1 CHARGE-TRANSPORTING INK COMPOSITION AND SURFACE-TREATED METAL OXIDE NANOPARTICLE SOL 日産化学株式会社 2025-02-27 WO disclosed
WO-2025033132-A1 CHARGE-TRANSPORTING VARNISH AND METHOD FOR PRODUCING SAME 日産化学株式会社 2025-02-13 WO disclosed
US-20110079273-A1 PHOTOVOLTAIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-04-07 US disclosed
US-20110036971-A1 PHOTOVOLTAIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-02-17 US disclosed
US-20100308306-A1 Use of a Metal Complex as a P-Dopant for an Organic Semiconductive Matrix Material, Organic Semiconductor Material, and Organic Light-Emitting Diodes OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-12-09 US disclosed
US-20100243998-A1 SEMICONDUCTOR MATERIAL AND ORGANIC RECTIFIER DIODE NOVALED GMBH (DE) 2010-09-30 US disclosed
WO-2010097433-A1 QUINONE COMPOUNDS AS DOPANTS IN ORGANIC ELECTRONICS BASF SE (DE) 2010-09-02 WO disclosed
WO-2010079051-A1 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2010-07-15 WO disclosed
WO-2009089472-A2 PHOTOVOLTAIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-07-16 WO disclosed
WO-2009089470-A2 PHOTOVOLTAIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 PDK2 2756/4885ABL1 917/4885ABCB1 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.