SCHEMBL18522285

SCHEMBL18522285

C=C(C)C(=O)Oc1ccc(-c2ccc(OC)c(F)c2)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.44
PTGS2 P35354 7/20 0.44
PRKCZ Q05513 1/20 0.44
PTGS1 P23219 4/20 0.43
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
TDP2 O95551 1/20 0.41
ERN1 O75460 1/20 0.40
XDH P47989 1/20 0.39
FFAR1 O14842 1/20 0.38
CD274 Q9NZQ7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196858 0.95 AR (0.42) ARPTGS2PRKCZPTGS1LMNA
SCHEMBL9607891 0.93 AR (0.36) ARPTGS2PRKCZPTGS1LMNA
SCHEMBL26144195 0.91 AKR1C3 (0.36) ARPTGS2PRKCZPTGS1LMNA
SCHEMBL26144205 0.87 AKR1C3 (0.39) ARPTGS2PRKCZPTGS1XDH
SCHEMBL23507808 0.86 PRKCZ (0.33) ARPTGS2PRKCZPTGS1
SCHEMBL18435889 0.86 ERN1 (0.33) ARPTGS2PRKCZPTGS1ERN1
SCHEMBL18869421 0.86 ERN1 (0.49) ARPTGS2PTGS1LMNAMAPK1
SCHEMBL18869267 0.86 FFAR4 (0.37) ARPTGS2PTGS1LMNAMAPK1
SCHEMBL22600373 0.85 ALOX5 (0.33) ARPTGS2PRKCZPTGS1ERN1
SCHEMBL20862845 0.85 FFAR4 (0.33) ARPTGS2PRKCZPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551723-B1 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2023-09-20 EP disclosed
EP-3933009-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-08-16 EP disclosed
EP-3870671-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-08-09 EP disclosed
EP-3839008-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-07-26 EP disclosed
EP-4209566-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-4209567-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-4209568-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-3628721-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
EP-3944011-A1 LIQUID-CRYSTAL DISPLAY Merck Patent GmbH (DE) 2022-01-26 EP disclosed
EP-3933009-A1 LIQUID CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-01-05 EP disclosed
EP-2886627-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2019-05-15 EP disclosed
EP-2990460-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-04-03 EP disclosed
EP-2725083-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2019-03-27 EP disclosed
EP-2607451-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2019-01-23 EP disclosed
EP-3428246-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2019-01-16 EP disclosed
EP-2985334-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-20 EP disclosed
EP-3260518-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-27 EP disclosed
EP-3029127-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed
EP-3257916-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-20 EP disclosed
EP-3130651-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-15 EP disclosed