Sugi Predict

Sugi Predict / Compounds / SCHEMBL1852285

SCHEMBL1852285

SCHEMBL1852285

CC(C)(C)OC(=O)C1CCN(N)C1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 1/20 0.48
▸ HPGD P15428 1/20 0.41
▸ RECQL P46063 1/20 0.39
▸ MEN1 O00255 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ TSHR P16473 1/20 0.37
▸ STS P08842 5/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.35
▸ PTPN2 P17706 1/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ PTPN6 P29350 1/20 0.35
▸ CTSK P43235 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ CHRM2 P08172 1/20 0.34
▸ CHRM1 P11229 1/20 0.34
▸ CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183835 1.00 HRH3 (0.48) HRH3HPGDRECQLMEN1ALDH1A1
SCHEMBL222318 1.00 HRH3 (0.48) HRH3HPGDRECQLMEN1ALDH1A1
Hydrochloric Acid SCHEMBL34473243 0.98 HRH3 (0.47) HRH3HPGDRECQLMEN1ALDH1A1
Formaldehyde SCHEMBL9013379 0.97 HRH3 (0.46) HRH3HPGDRECQLMEN1ALDH1A1
SCHEMBL1707724 0.90 HRH3 (0.42) HRH3HPGDRECQLMEN1ALDH1A1
SCHEMBL16666240 0.90 HRH3 (0.42) HRH3HPGDRECQLMEN1ALDH1A1
SCHEMBL5007737 0.90 HRH3 (0.42) HRH3HPGDRECQLMEN1ALDH1A1
SCHEMBL374206 0.89 HRH3 (0.54) HRH3HPGDRECQLMEN1ALDH1A1
Hydrochloric Acid SCHEMBL31015156 0.88 HRH3 (0.41) HRH3HPGDRECQLMEN1ALDH1A1
Hydrochloric Acid SCHEMBL28556920 0.88 HRH3 (0.41) HRH3HPGDRECQLMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117102-A The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino pyrrolidine 无锡乾浩生物医药有限公司 2016-11-16 — — CN claimed
US-20240190864-A1 Bruton's Tyrosine Kinase (BTK) INHIBITOR AND APPLICATION THEREOF YA THERAPEUTICS INC (CN) 2024-06-13 — — US disclosed
CN-118084881-A PROTAC small molecules, pharmaceutical composition and application thereof 南京正济医药研究有限公司 2024-05-28 — — CN disclosed
CN-111087409-B Quinolone compound and preparation method and application thereof 江阴安博生物医药有限公司 2021-06-08 — — CN disclosed
CN-111087409-A Quinolone compound and preparation method and application thereof 江阴安博生物医药有限公司 2020-05-01 — — CN disclosed
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof UNIVERSITY OF WASHINGTON (US) 2019-09-03 — — US disclosed
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-01-31 — — US disclosed
WO-2017127627-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-07-27 — — WO disclosed
CN-106117102-A The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino pyrrolidine 无锡乾浩生物医药有限公司 2016-11-16 — — CN disclosed
CN-106117102-A The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino pyrrolidine 无锡乾浩生物医药有限公司 2016-11-16 — — CN disclosed
EP-0723545-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-07-31 — — EP disclosed
CN-1117491-A 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative NORTHERN CONTINENTAL CO LTD (JP) 1996-02-28 — — CN disclosed
WO-1995010519-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1995-04-20 — — WO disclosed
CN-1079744-A 7-oxo-7H-pyrido [1,2,3 ,-d, e] [1,4] benzoxazine-6-carboxylic acids and ester thereof BAYER AG (DE) 1993-12-22 — — CN disclosed
CN-1019668-B process for preparing quinolone carboxylic acid derivatives KYORIN SEIYAKU KK (JP) 1992-12-30 — — CN disclosed
CN-1009830-B PROCESS FOR PREPARATION OF QUINOLONECARBOXYLIC ACID DERIV. KYORIN SEIYAKU KK (JP) 1990-10-03 — — CN disclosed
CN-87101984-A Carbostyril carboxylic acid derivatives and preparation method thereof — 1987-10-07 — — CN disclosed
CN-87101731-A Carbostyril carboxylic acid derivatives that replaces on No. 8 positions and preparation method thereof — 1987-09-16 — — CN disclosed
CN-86104414-A The preparation method of Carbostyril carboxylic acid derivatives — 1987-02-04 — — CN disclosed
EP-0160578-A1 1,8-Naphthyridine derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1985-11-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF TSPO, GBA1, NLN HRH3 1963/4885HPGD 1598/4885RECQL 2572/4885
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof TSPO, GBA1, NLN HRH3 1963/4885HPGD 1598/4885RECQL 2572/4885
US-20240190864-A1 Bruton's Tyrosine Kinase (BTK) INHIBITOR AND APPLICATION THEREOF BTK, SYK, LYN HRH3 2499/4885HPGD 3246/4885RECQL 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.