SCHEMBL374206

SCHEMBL374206

CC(C)(C)OC(=O)C1CCN(N)CC1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.54
HPGD P15428 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.37
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN6 P29350 1/20 0.37
TP53 P04637 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28219724 0.98 HRH3 (0.53) HRH3HPGDKMT2AMEN1ALDH1A1
Piperazine SCHEMBL28869552 0.92 HRH3 (0.48) HRH3HPGDKMT2AMEN1ALDH1A1
SCHEMBL183835 0.89 HRH3 (0.48) HRH3HPGDKMT2AMEN1ALDH1A1
SCHEMBL1852285 0.89 HRH3 (0.48) HRH3HPGDKMT2AMEN1ALDH1A1
SCHEMBL222318 0.89 HRH3 (0.48) HRH3HPGDKMT2AMEN1ALDH1A1
Hydrochloric Acid SCHEMBL34473243 0.87 HRH3 (0.47) HRH3HPGDKMT2AMEN1ALDH1A1
Formaldehyde SCHEMBL9013379 0.86 HRH3 (0.46) HRH3HPGDKMT2AMEN1ALDH1A1
Toluene SCHEMBL27527909 0.85 HRH3 (0.43) HRH3KMT2AMEN1ALDH1A1
SCHEMBL4055980 0.82 HRH3 (0.55) HRH3HPGDKMT2AMEN1ALDH1A1
SCHEMBL10274867 0.82 HRH3 (0.55) HRH3HPGDKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977850-A Urea derivative containing aryl sulfonamide structure, and preparation method and application thereof 沈阳药科大学 2025-05-13 CN claimed
CN-119326725-A Preparation method of ertapenem sodium for injection 海南合瑞制药股份有限公司 2025-01-21 CN claimed
CN-119119066-A Galanthamine analogue, and preparation method and application thereof 沈阳药科大学 2024-12-13 CN claimed
CN-118146226-A Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof 贵州大学 2024-06-07 CN claimed
CN-118146165-A 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2024-06-07 CN claimed
CN-118084865-A Pyrimidine compound containing aminopiperidine structure, and preparation method and application thereof 贵州大学 2024-05-28 CN claimed
CN-113968824-B 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2024-01-19 CN claimed
CN-117143091-A HBV core protein degradation agent based on hydrophobic tag technology and preparation method and application thereof 山东大学 2023-12-01 CN claimed
CN-116836153-A CDK9-Cyclin T1 protein interaction inhibitor and application thereof 厦门大学 2023-10-03 CN claimed
CN-115232130-A APN and AKT double-target-point inhibitor and preparation method and application thereof 山东大学 2022-10-25 CN claimed
CN-113607831-B Detection method of 4-Boc-aminopiperidine related substance 河北国龙制药有限公司 2022-04-08 CN claimed
CN-114014866-A 5, 7-dihydrofuro [3,4-d ] pyrimidine compound and preparation method and application thereof 山东大学 2022-02-08 CN claimed
CN-113968824-A 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2022-01-25 CN claimed
CN-113607831-A Detection method of 4-Boc-aminopiperidine related substance 河北国龙制药有限公司 2021-11-05 CN claimed
CN-107805218-B Method for preparing 4-Boc-aminopiperidine 上海皓伯化工科技有限公司 2020-06-02 CN claimed
CN-106883232-B A kind of derivative and the preparation method and application thereof of non-that alkene -3- ketone of azepine 苏州康润医药有限公司 2019-01-22 CN claimed
CN-107556318-A A kind of azolopyrimidines containing piperidines and preparation method and application 山东大学 2018-01-09 CN claimed
CN-106146385-A A kind of synthetic method of triglyceride transfer protein enzyme inhibitor 天津药物研究院有限公司 2016-11-23 CN claimed
CN-101484424-A Therapeutic compounds HELICON THERAPEUTICS INC (US) 2009-07-15 CN claimed
US-5378691-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US claimed