SCHEMBL18523372

SCHEMBL18523372

CCOC(=O)C(C(C)C)C(O)C=C(C)C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
GLO1 Q04760 1/20 0.33
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18523388 0.84 TSHR (0.40) ALDH1A1ALOX15
SCHEMBL18523390 0.81 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10CYP2D6CYP2C19
SCHEMBL18546633 0.81 SMN1; SMN2 (0.41)
SCHEMBL18523387 0.81 SMN1; SMN2 (0.41)
SCHEMBL18523385 0.80 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10CYP2D6CYP2C19
SCHEMBL2984138 0.79 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10CYP2D6CYP2C19
SCHEMBL28127339 0.79 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10CYP2D6CYP2C19
SCHEMBL235785 0.77 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10CYP2C19HPGD
SCHEMBL9054019 0.77 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10CYP2C19HPGD
Ammonia Solution, Strong SCHEMBL27560423 0.75 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106467464-B (E) -2-isopropyl-5-methyl-3, 5-hexadienoic acid ester compound and production method and application thereof 信越化学工业株式会社 2020-12-29 CN disclosed
EP-3133053-B1 (E)-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHINETSU CHEMICAL CO (JP) 2018-01-17 EP disclosed
EP-3133053-B1 (E)-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHINETSU CHEMICAL CO (JP) 2018-01-17 EP disclosed
US-9725400-B2 (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound, method for producing the same, and methods for producing (E)-2-isopropyl-5-methyl-3,5-hexadienol and (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate by using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-08 US disclosed
US-9725400-B2 (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound, method for producing the same, and methods for producing (E)-2-isopropyl-5-methyl-3,5-hexadienol and (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate by using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-08 US disclosed
US-9725400-B2 (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound, method for producing the same, and methods for producing (E)-2-isopropyl-5-methyl-3,5-hexadienol and (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate by using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-08 US disclosed
CN-106467464-A (E) 2 isopropyl 5 methyl 3,5 hexadienoic acid ester compounds and its production method and produce (E) 2 isopropyl 5 methyl 3 using it, 5 hexadienols and the method for (E) 2 isopropyl 5 methyl 3,5 hexadienyl carboxylate 信越化学工业株式会社 2017-03-01 CN disclosed
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
EP-3133053-A1 (E)-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-22 EP disclosed
EP-3133053-A1 (E)-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHBG, GNE, PGRMC2 ALDH1A1 1560/4885LMNA 3140/4885HSD17B10 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.