Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18523535 | 0.94 | CA2 (0.53) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18541392 | 0.88 | CA2 (0.47) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18525393 | 0.84 | ERN1 (0.46) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17293919 | 0.83 | CA2 (0.56) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16024770 | 0.82 | CA2 (0.57) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16996689 | 0.82 | CA2 (0.67) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9056140 | 0.78 | CA2 (0.56) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL240515 | 0.78 | CA2 (0.80) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29602570 | 0.78 | CA2 (0.80) | CA2CA1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16014947 | 0.77 | CA2 (0.46) | CA2CA1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | EVONIK DEGUSSA GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-3133189-A1 | METHOD FOR THE PREPARATION OF ASYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131607-B2 | Process for preparing unsymmetric OCO pincer ligands from the group of the M-terphenyl compounds | COMT, MSMO1, TYR | CA2 1001/4885CA1 2238/4885ALDH1A1 3779/4885 |
| US-20170050910-A1 | PROCESS FOR PREPARING UNSYMMETRIC OCO PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | COMT, MSMO1, TYR | CA2 1001/4885CA1 2238/4885ALDH1A1 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.