Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801089 | 0.88 | ERN1 (0.45) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL7520392 | 0.87 | ERN1 (0.57) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL890444 | 0.85 | ERN1 (0.49) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL18523532 | 0.84 | CA2 (0.49) | ERN1PTPN1GAAMAPTALDH1A1 | |
| SCHEMBL16024748 | 0.83 | ERN1 (0.50) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL18535615 | 0.83 | ERN1 (0.44) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL18523536 | 0.82 | ERN1 (0.41) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL890428 | 0.81 | ALOX5 (0.50) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL18527403 | 0.80 | ERN1 (0.41) | ERN1TNKS2ACHEPTGS2ALOX5 | |
| SCHEMBL890499 | 0.80 | ACHE (0.55) | ERN1TNKS2ACHEPTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131623-B2 | Process for preparing symmetric pincer ligands from the group of the M-terphenyl compounds | EVONIK DEGUSSA GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| EP-3133054-B1 | METHOD FOR THE PREPARATION OF SYMMETRICAL PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-20170050918-A1 | PROCESS FOR PREPARING SYMMETRIC PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050918-A1 | PROCESS FOR PREPARING SYMMETRIC PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| US-20170050918-A1 | PROCESS FOR PREPARING SYMMETRIC PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| EP-3133054-A1 | METHOD FOR THE PREPARATION OF SYMMETRICAL PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-3133054-A1 | METHOD FOR THE PREPARATION OF SYMMETRICAL PINCER LIGANDS FROM THE GROUP OF M TERPHENYL COMPOUNDS | Evonik Degussa GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131623-B2 | Process for preparing symmetric pincer ligands from the group of the M-terphenyl compounds | C1R, C3AR1, M6PR | ERN1 2752/4885TNKS2 1039/4885ACHE 666/4885 |
| US-20170050918-A1 | PROCESS FOR PREPARING SYMMETRIC PINCER LIGANDS FROM THE GROUP OF THE M-TERPHENYL COMPOUNDS | C1R, M6PR, C3AR1 | ERN1 2696/4885TNKS2 958/4885ACHE 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.