Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443966 | 0.90 | KMT2A (0.55) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL18523654 | 0.89 | KMT2A (0.55) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL18523270 | 0.88 | KMT2A (0.45) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL21444300 | 0.88 | KMT2A (0.51) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL18523766 | 0.86 | KMT2A (0.53) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL26813288 | 0.84 | ALDH1A1 (0.41) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL22432366 | 0.82 | KDM4E (0.36) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL18502515 | 0.82 | RAB9A (0.37) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL18524000 | 0.82 | KMT2A (0.54) | KMT2AMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL23816798 | 0.81 | HSP90AA1 (0.38) | KMT2AMAPTNPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130591-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Electronics Co., Ltd. (KR) | 2017-02-15 | — | — | EP | disclosed |