Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154592 | 0.79 | KMT2A (0.55) | SLC6A2TP53KDM4EKMT2AMAPT | |
| SCHEMBL29378766 | 0.79 | KMT2A (0.55) | SLC6A2TP53KDM4EKMT2AMAPT | |
| Ammonia Solution, Strong SCHEMBL28142197 | 0.77 | KMT2A (0.53) | SLC6A2TP53KDM4EKMT2AMAPT | |
| SCHEMBL7678437 | 0.74 | SLC6A2 (0.44) | SLC6A2TP53KDM4EKMT2ATSHR | |
| SCHEMBL14575430 | 0.74 | KMT2A (0.36) | KDM4EKMT2ATSHRMAPTMEN1 | |
| Cyanide SCHEMBL6526282 | 0.74 | KMT2A (0.50) | SLC6A2TP53KDM4EKMT2AMAPT | |
| SCHEMBL6114342 | 0.73 | SLC6A2 (0.43) | SLC6A2TP53KDM4EKMT2ATSHR | |
| SCHEMBL14487047 | 0.73 | KMT2A (0.44) | SLC6A2TP53KDM4EKMT2ATSHR | |
| SCHEMBL3229178 | 0.73 | SLC6A2 (0.43) | SLC6A2TP53KDM4EKMT2ATSHR | |
| SCHEMBL3008864 | 0.73 | DAO (0.52) | SLC6A2TP53KDM4EKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137074-B1 | PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, COMPOSITIONS, AND USES RELATED THERETO | UNIV EMORY (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-3130595-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSIS COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | Samsung Electronics Co., Ltd. (KR) | 2017-02-15 | — | — | EP | disclosed |
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |