Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PON1 | P27169 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452878 | 0.84 | KMT2A (0.35) | RAPGEF4LMNAMAPTNPSR1PON1 | |
| SCHEMBL28900653 | 0.82 | LMNA (0.38) | RAPGEF4LMNAMAPTNPSR1THRB | |
| SCHEMBL2935751 | 0.82 | LMNA (0.41) | LMNAMAPTNPSR1THRBTP53 | |
| Toluene SCHEMBL14859755 | 0.82 | LMNA (0.41) | RAPGEF4LMNAMAPTNPSR1THRB | |
| SCHEMBL52073 | 0.79 | HTT (0.42) | RAPGEF4LMNAMAPTNPSR1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL2325415 | 0.79 | SMN1; SMN2 (0.46) | LMNAMAPTNPSR1THRBTP53 | |
| Sulfuric Acid SCHEMBL1828230 | 0.77 | SMN1; SMN2 (0.44) | LMNAMAPTNPSR1THRBTP53 | |
| SCHEMBL295578 | 0.77 | SMN1; SMN2 (0.44) | LMNAMAPTNPSR1THRBTP53 | |
| SCHEMBL411942 | 0.77 | SMN1; SMN2 (0.44) | LMNAMAPTNPSR1THRBTP53 | |
| Phenylmethanesulfonic Acid SCHEMBL3826460 | 0.77 | LMNA (0.39) | LMNAMAPTNPSR1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935388-B1 | HYDROLYSIS-RESISTANT POLYURETHANE MOULDED ARTICLES MADE OF POLYESTER POLYURETHANE | BASF SE (DE) | 2017-02-22 | — | — | EP | disclosed |