Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | PON1 | P27169 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52073 | 0.88 | HTT (0.42) | LMNAMAPTNPSR1GAAALDH1A1 | |
| SCHEMBL4457301 | 0.86 | MAPT (0.52) | LMNAMAPTNPSR1THRBTP53 | |
| Toluene SCHEMBL14859755 | 0.85 | LMNA (0.41) | LMNAMAPTNPSR1THRBTP53 | |
| SCHEMBL7463637 | 0.84 | MEN1 (0.61) | MAPTNPSR1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7457714 | 0.84 | MEN1 (0.61) | MAPTNPSR1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7462985 | 0.84 | MEN1 (0.61) | MAPTNPSR1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3038116 | 0.83 | CA1 (0.35) | LMNAMAPTNPSR1GAAALDH1A1 | |
| Phenylmethanesulfonic Acid SCHEMBL3826460 | 0.83 | LMNA (0.39) | LMNAMAPTNPSR1THRBTP53 | |
| Sulfuric Acid SCHEMBL2325415 | 0.82 | SMN1; SMN2 (0.46) | LMNAMAPTNPSR1THRBTP53 | |
| SCHEMBL18525262 | 0.82 | RAPGEF4 (0.39) | LMNAMAPTNPSR1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100296226-A1 | ELECTRIC DOUBLE LAYER CAPACITOR | SHOWA DENKO K.K. (JP) | 2010-11-25 | — | — | US | disclosed |
| EP-1182197-A1 | Single step preparation of ionic fluids | Solvent Innovation GmbH (DE) | 2002-02-27 | — | — | EP | disclosed |