SCHEMBL18525407

SCHEMBL18525407

Cc1cc2cccnc2n1I

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 5/20 0.39
ATM Q13315 3/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2D6 P10635 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.38
CCR1 P32246 3/20 0.38
CCR8 P51685 3/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
SLC22A12 Q96S37 2/20 0.37
CCR5 P51681 2/20 0.37
PSMD14 O00487 1/20 0.37
COPS5 Q92905 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 2/20 0.35
HTT P42858 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8324162 0.78 CCR1 (0.43) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL18525218 0.77 PSMD14 (0.44) ALDH1A1KDM4EATMCYP3A4CYP2D6
Ammonia Solution, Strong SCHEMBL28471192 0.77 CCR1 (0.42) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL19233630 0.77 ALDH1A1 (0.40) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL18510247 0.77 KDM4E (0.56) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL18511094 0.77 KDM4E (0.39) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL19121164 0.74 KDM4E (0.47) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL19121794 0.74 KDM4E (0.40) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL28575987 0.73 SLC22A12 (0.38) ALDH1A1KDM4EATMCYP3A4CYP2D6
SCHEMBL27330066 0.73 ATM (0.39) ALDH1A1KDM4EATMCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3130595-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSIS COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2017-02-15 EP disclosed