Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TGM1 | P22735 | 1/20 | 0.49 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866574 | 0.81 | PTPN1 (0.53) | RAB9ANPC1KDM4EF13A1TGM2 | |
| SCHEMBL5629535 | 0.81 | RAB9A (0.62) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL28703760 | 0.80 | RAB9A (0.81) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL29376441 | 0.80 | RAB9A (0.81) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL1558713 | 0.80 | RAB9A (0.70) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL16095289 | 0.80 | TGM2 (0.44) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL18489422 | 0.80 | TGM2 (0.46) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL30421156 | 0.79 | RAB9A (0.65) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL5629538 | 0.79 | RAB9A (0.65) | RAB9ANPC1KDM4EHTTATM | |
| SCHEMBL17315853 | 0.78 | RAB9A (0.59) | RAB9ANPC1KDM4EHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027343-A1 | CGRP RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2017-02-16 | — | — | WO | disclosed |