Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185150 | 0.87 | GCK (0.71) | GCKKMT2ATDP1 | |
| SCHEMBL184693 | 0.86 | GCK (0.64) | GCKKMT2A | |
| SCHEMBL185473 | 0.81 | GCK (0.57) | GCKKMT2A | |
| SCHEMBL184635 | 0.80 | GCK (0.75) | GCKKMT2A | |
| SCHEMBL184841 | 0.79 | GCK (0.75) | GCKKMT2A | |
| SCHEMBL185053 | 0.79 | GCK (0.58) | GCKKMT2A | |
| SCHEMBL185060 | 0.79 | GCK (0.73) | GCKKMT2A | |
| SCHEMBL184558 | 0.78 | GCK (0.58) | GCK | |
| SCHEMBL184721 | 0.78 | GCK (1.00) | GCKKMT2A | |
| SCHEMBL3779285 | 0.78 | GCK (0.70) | GCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | claimed |
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |