Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.31 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526226 | 0.89 | IP6K1 (0.36) | SERPINE1IP6K1 | |
| SCHEMBL18526228 | 0.83 | SERPINE1 (0.31) | SERPINE1 | |
| SCHEMBL18526246 | 0.82 | IP6K1 (0.34) | SERPINE1IP6K1KDM4EMEN1ALDH1A1 | |
| SCHEMBL18525778 | 0.82 | IP6K1 (0.35) | SERPINE1IP6K1KDM4EMEN1ALDH1A1 | |
| SCHEMBL26751936 | 0.81 | IP6K1 (0.34) | SERPINE1IP6K1KDM4EMEN1ALDH1A1 | |
| SCHEMBL24012428 | 0.79 | IP6K1 (0.36) | SERPINE1IP6K1KDM4EMEN1ALDH1A1 | |
| SCHEMBL18526318 | 0.78 | — | — | |
| SCHEMBL18526229 | 0.77 | PDK2 (0.30) | — | |
| SCHEMBL18525805 | 0.76 | MAPT (0.33) | SERPINE1IP6K1KDM4EMEN1ALDH1A1 | |
| SCHEMBL18526316 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170045501-A1 | AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS | HOWARD HUGHES MEDICAL INSTITUTE | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170045501-A1 | AZETIDINE-SUBSTITUTED FLUORESCENT COMPOUNDS | AANAT, HNMT, CHAT | SERPINE1 3254/4885IP6K1 4353/4885KDM4E 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.