Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17776425 | 1.00 | CNR1 (0.55) | CNR1ALDH1A1HTTCHRM1KDM4E | |
| SCHEMBL3700677 | 1.00 | CNR1 (0.55) | CNR1ALDH1A1HTTCHRM1KDM4E | |
| SCHEMBL26802536 | 0.98 | ALDH1A1 (0.54) | CNR1ALDH1A1HTTCHRM1KDM4E | |
| SCHEMBL1072709 | 0.98 | ALDH1A1 (0.54) | CNR1ALDH1A1HTTCHRM1KDM4E | |
| SCHEMBL25432324 | 0.96 | CNR1 (0.55) | CNR1ALDH1A1HTTCHRM1MAPT | |
| SCHEMBL7131843 | 0.92 | CNR1 (0.61) | CNR1CHRM1KMT2ACHRM3BCHE | |
| SCHEMBL22808475 | 0.92 | CNR1 (0.61) | CNR1CHRM1KMT2ACHRM3BCHE | |
| SCHEMBL16333765 | 0.90 | PTGS2 (0.59) | CNR1HPGDKMT2ANPSR1 | |
| SCHEMBL18389818 | 0.86 | CHRM1 (0.63) | CNR1CHRM1CHRM3 | |
| SCHEMBL18704994 | 0.84 | CHRM1 (0.67) | CNR1ALDH1A1CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036009-A | Substituted pyrrolidines and their use in the treatment of cystic fibrosis | 艾伯维公司 | 2019-07-19 | — | — | CN | claimed |
| WO-2023105387-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-110036009-A | Substituted pyrrolidines and their use in the treatment of cystic fibrosis | 艾伯维公司 | 2019-07-19 | — | — | CN | disclosed |
| EP-2499132-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-15 | — | — | EP | disclosed |