SCHEMBL18528346

SCHEMBL18528346

C=CCCCCCCCCOC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 2/20 0.38
LPAR2 Q9HBW0 1/20 0.38
TSHR P16473 1/20 0.34
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9084950 0.82 LMNA (0.32) LMNA
SCHEMBL5269252 0.82
SCHEMBL1118354 0.78 LPAR3 (0.44) LPAR3LPAR2TSHRTRPA1ALDH1A1
SCHEMBL34470893 0.78 LPAR3 (0.44) LPAR3LPAR2TSHRTRPA1ALDH1A1
SCHEMBL5269630 0.77
SCHEMBL1118373 0.76 LPAR3 (0.41) LPAR3LPAR2TSHRTRPA1ALDH1A1
SCHEMBL5831832 0.75 LMNA (0.33) LMNA
SCHEMBL29132605 0.75 CES1 (0.44) LPAR3LPAR2TSHRMAPT
SCHEMBL9551594 0.75 LPAR3 (0.41) LPAR3LPAR2TSHRTRPA1ALDH1A1
SCHEMBL18528345 0.73 LPAR3 (0.37) LPAR3LPAR2TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10758483-B2 Fluoropolymer emulsions with perhalogenated stabilizer for the delivery of hydrophobic drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-09-01 US disclosed
US-10426727-B2 Fluoropolymer emulsions with branched semifluorinated block copolymer or phospholipid surfactant for the delivery of hydrophobic drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-10-01 US disclosed
US-20170100336-A1 Fluoropolymer Emulsions with Perhalogenated Stabilizer for the Delivery of Hydrophobic Drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-04-13 US disclosed
US-20170049699-A1 Fluoropolymer Emulsions with Branched Semifluorinated Block Copolymer or Phospholipid Surfactant for the Delivery of Hydrophobic Drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10426727-B2 Fluoropolymer emulsions with branched semifluorinated block copolymer or phospholipid surfactant for the delivery of hydrophobic drugs FFAR3, FFAR1, FAU LPAR3 84/4885LPAR2 157/4885TSHR 1016/4885
US-20170049699-A1 Fluoropolymer Emulsions with Branched Semifluorinated Block Copolymer or Phospholipid Surfactant for the Delivery of Hydrophobic Drugs FFAR3, FFAR1, FAU LPAR3 84/4885LPAR2 157/4885TSHR 1016/4885
US-10758483-B2 Fluoropolymer emulsions with perhalogenated stabilizer for the delivery of hydrophobic drugs PFN1, FFAR1, FAU LPAR3 169/4885LPAR2 200/4885TSHR 1632/4885
US-20170100336-A1 Fluoropolymer Emulsions with Perhalogenated Stabilizer for the Delivery of Hydrophobic Drugs PFN1, FFAR1, FAU LPAR3 169/4885LPAR2 200/4885TSHR 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.