Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806884 | 0.88 | CNR2 (0.37) | CNR2HTR1ADRD2DRD4DRD3 | |
| SCHEMBL14856682 | 0.86 | FAAH (0.36) | CNR2FAAHTRPV1HTR1ADRD2 | |
| SCHEMBL185420 | 0.85 | CNR2 (0.34) | CNR2FAAHTRPV1EGFRKDR | |
| SCHEMBL2805079 | 0.85 | CNR2 (0.39) | CNR2HTR1ADRD2DRD4DRD3 | |
| SCHEMBL14856670 | 0.85 | FAAH (0.35) | CNR2FAAHTRPV1HTR1ADRD2 | |
| SCHEMBL14856724 | 0.85 | FAAH (0.35) | CNR2FAAHTRPV1HTR1ADRD2 | |
| SCHEMBL186591 | 0.84 | CNR2 (0.36) | CNR2FAAHTRPV1EGFRKDR | |
| SCHEMBL14856433 | 0.84 | CNR2 (0.33) | CNR2FAAHTRPV1 | |
| SCHEMBL14856688 | 0.83 | FAAH (0.34) | CNR2FAAHTRPV1HTR1ADRD2 | |
| SCHEMBL2809358 | 0.83 | BDKRB1 (0.40) | CNR2EGFRKDRBDKRB1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |