SCHEMBL14856433

SCHEMBL14856433

O=C(NC1(C(=O)NCc2ccc(Nc3ccc(Br)cc3C(F)(F)F)cn2)CC1)Oc1cc(O)nc(O)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.33
FAAH O00519 1/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185934 0.91 CNR2 (0.35) CNR2TRPV1
SCHEMBL186591 0.90 CNR2 (0.36) CNR2FAAHTRPV1
SCHEMBL2810180 0.87 CNR2 (0.36) CNR2
SCHEMBL185287 0.84 CNR2 (0.34) CNR2FAAHTRPV1
SCHEMBL14856682 0.84 FAAH (0.36) CNR2FAAHTRPV1
SCHEMBL185420 0.84 CNR2 (0.34) CNR2FAAHTRPV1
SCHEMBL2805079 0.83 CNR2 (0.39) CNR2
SCHEMBL14856670 0.83 FAAH (0.35) CNR2FAAHTRPV1
SCHEMBL14856724 0.83 FAAH (0.35) CNR2FAAHTRPV1
SCHEMBL2804950 0.81 CNR2 (0.39) CNR2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401256-B1 Compounds as bradykinin B1 antagonists BOEHRINGER INGELHEIM INT (DE) 2013-04-17 EP disclosed