Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121393 | 0.92 | NPC1 (0.71) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL18528796 | 0.90 | NPC1 (0.69) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL12937173 | 0.89 | NPC1 (0.73) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL12937136 | 0.89 | NPC1 (0.58) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL22116712 | 0.88 | NPC1 (0.57) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5754354 | 0.88 | KDM4E (0.71) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6403119 | 0.86 | NPC1 (0.55) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL31512896 | 0.86 | KDM4E (0.58) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL21777008 | 0.86 | KDM4E (0.62) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6296345 | 0.86 | NPC1 (0.55) | NPC1KDM4EHSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9811010-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20170052464-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2017-02-23 | — | — | US | disclosed |