SCHEMBL18529

SCHEMBL18529

[c]1ccc2cc3ccccc3cc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP3A4 P08684 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37
HIF1A Q16665 2/20 0.37
ALOX15 P16050 1/20 0.37
HBB P68871 1/20 0.37
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36
ACHE P22303 1/20 0.36
CYP2A6 P11509 6/20 0.35
ALOX12 P18054 1/20 0.35
NQO2 P16083 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CYP1A2 P05177 3/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21461252 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1CASP1
SCHEMBL29101792 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1CASP1
SCHEMBL25451 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1CASP1
SCHEMBL5049192 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1CASP1
SCHEMBL70257 0.92
SCHEMBL559813 0.92
SCHEMBL508946 0.90 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP3A4TDP1HIF1A
SCHEMBL1044899 0.89
SCHEMBL1413199 0.89
SCHEMBL3241848 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12426 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US claimed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US claimed
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-13 US claimed
EP-4381009-A1 POLYOLEFIN FORMULATION CONTAINING COMBINATION OF VOLTAGE STABILIZER COMPOUNDS Dow Global Technologies LLC (US) 2024-06-12 EP claimed
CN-112079786-B Compound, organic electronic light-emitting device containing compound and application of compound 北京鼎材科技有限公司 2024-05-21 CN claimed
WO-2024099269-A1 ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF 华东师范大学 2024-05-16 WO claimed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN claimed
EP-3378853-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2024-04-17 EP claimed
CN-112094169-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-03-26 CN claimed
CN-112441977-B Compound, application thereof and organic electroluminescent device comprising compound 北京鼎材科技有限公司 2024-03-19 CN claimed
US-5219692-A Electrophotographic photoconductors and tertiary amine compounds having condensed polycyclic group for use in the same RICOH COMPANY, LTD. (JP) 1993-06-15 US claimed
US-5187056-A Novel yellow coupler FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US claimed
EP-0204285-B1 IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-15 EP claimed
EP-0306868-B1 PROCESS FOR THE PREPARATION OF 1-ALKYL IMIDAZOLES BASF Aktiengesellschaft (DE) 1991-12-27 EP claimed
US-4725601-A Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-16 US claimed
EP-0062611-B1 PHOTOPOLYMERISATION PROCESS CIBA-GEIGY AG (CH) 1985-04-24 EP claimed
US-4413052-A Photopolymerization process employing compounds containing acryloyl group and anthryl group CIBA-GEIGY CORPORATION (US) 1983-11-01 US claimed
EP-0062611-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP claimed
US-4117239-A PROCESS FOR PREPARATION OF 2-ANTHRYL AND SUBSTITUTED 2-ANTHRYL FUNCTIONAL MONOMERS AND POLYMERS XEROX CORPORATION (US) 1978-09-26 US claimed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 US claimed